Full list of peer-reviewed publications

  • Giampaolo Morciano*, Natalia Naumova*, Piotr Koprowski, Sara Valente, Vilma A. Sardão, Yaiza Potes, Alessandro Rimessi, Mariusz R. Wieckowski$ and Paulo J. Oliveira$ “The Mitochondrial Permeability Transition: An Experimentally-driven Portrait in Movement” Biological Reviews - in press IF = 11.70; Wieckowski and Oliviera are both corresponding authors and share senior authorship.

  • Simone Patergnani, Massimo Bonora, Selene Ingusci, Maurizio Previati, Saverio Marchi, Silvia Zucchini, Mariasole Perrone, Mariusz R. Wieckowski, Massimiliano Castellazzi, Maura Pugliatti, Carlotta Giorgi, Michele Simonato, and Paolo Pinton "Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis" PNAS June 15, 2021; 118 (24) e2020078118; IF = 9.412

  • Lebiedzinska-Arciszewska M, Wojtczak L, Wieckowski MR. "An Update on Isolation of Functional Mitochondria from Cells for Bioenergetics Studies" Methods Mol Biol. 2021;2310:79-89.

  • Paulina Patalas-Krawczyk; Malinska Dominika; Jaroslaw Walczak; Monika Prill; Bernadeta Michalska; Karolina Drabik; Bjorn Titz; Yvan Eb-Levadoux; Thomas Schneider; Jedrzej Szymański; Julia Hoeng; Manuel Peitsch; Jerzy Duszyński; Joanna Szczepanowska; Carole Mathis; Mariusz R. Wieckowski “Effects of plant alkaloids on opening of the mitochondrial permeability transition pore” - Food and Chemical Toxicology - in press, IF = 4.679

  • Wieckowski MR, Pronicki M, Karkucinska-Wieckowska A. "Update on the Histoenzymatic Methods for Visualization of the Activity of Individual Mitochondrial Respiratory Chain Complexes in the Human Frozen Sections". Methods Mol Biol. 2021;2310:69-77.

  • A. Karkucinska-Wieckowska, I.C.M. Simoes, P. Kalinowski, M. Lebiedzinska-Arciszewska, K. Zieniewicz, P. Milkiewicz, M. Górska-Ponikowska, P. Pinton, A.N. Malik, M. Krawczyk, P.J. Oliveira, M.R. Wieckowski "Mitochondria, oxidative stress and Non-Alcoholic Fatty Liver Disease development: a complex relationship" European Journal of Clinical Investigations - in press, IF = 3.481

  • Alberto Danese, Sara Leo, Alessandro Rimessi, Mariusz R. Wieckowski, Francesco Fiorica, Carlotta Giorgi* and Paolo Pinton* “Cell death as a result of calcium signaling modulation: a cancer-centric prospective” BBA Molecular Cell Res. – in press, IF = 3.465

  • Ricardo Amorima, Inês Simões, Caroline Veloso, Adriana Carvalho, Rui F. Simões, Francisco B. Pereirad, Catarina Moraisa, Amália Juradoa, Mariusz R. Wieckowski, José Teixeira, Paulo J. Oliveira “Exploratory data analysis of cell and mitochondrial high-fat, high-sugar toxicity on human HepG2 cells” Nutrients - in press, IF = 4.546

  • M. Prill*, A. Karkucinska-Wieckowska*, M. Lebiedzinska-Arciszewska*, G. Morciano, A. Charzynska, P. Pinton, M. Dabrowski, M. Pronicki, W. Grajkowska$# and Wieckowski M. R.$# “Investigation of Ras and ShcA protein expression patterns in pediatric brain tumors” Journal of Clinical Medicine, 2021, 10(10), 2219., IF = 3.303

  • Daniela Ramaccini, Vanessa Montoya-Uribe, Femke Femke Aan, Lorenzo Modesti, Yaiza Potes, Mariusz R. Wieckowski, Irena Krga, Marija Glibetic, Paolo Pinton, Carlotta Giorgi, Michelle Matter "Mitochondrial function and dysfunction in Cardiomyopathy" Frontiers in Cell and Developmental Biology (Cellular Biochemistry) 2021 Jan 12;8:624216. doi: 10.3389/fcell.2020.624216; IF = 5.201

  • Alba Clara Sarti, Valentina Vultaggio-Poma, Simonetta Falzoni, Sonia Missiroli, Anna Lisa Giuliani, Paola Boldrini, Massimo Bonora, Francesco Faita, Nicole Di Lascio, Claudia Kusmic, Anna Solini, Salvatore Novello, Michele Morari, Marco Rossato, Mariusz R. Wieckowski, Carlotta Giorgi, Paolo Pinton and Francesco Di Virgilio ”The P2X7 receptor localizes to the mitochondria, modulates mitochondrial energy metabolism, and enhances physical performance" Function, Volume 2, Issue 2, 2021, zqab006, https://doi.org/10.1093/function/zqab006

  • Simone Patergnani, Saverio Marchi, Benjamin Delprat and Mariusz R. Wieckowski “Editorial: Organelles Relationships and Interactions: A Cancer Perspective” Frontiers in Cell and Developmental Biology (Signaling); 9:678307. doi: 10.3389/fcell.2021.678307 IF = 5.201

  • Giampaolo Morciano, Gaia Pedriali, Massimo Bonora, Rita Pavasini, Elisa Mikus, Simone Calvi, Matteo Bovolenta, Magdalena Lebiedzinska-Arciszewska, Mirko Pinotti, Alberto Albertini, Mariusz R. Wieckowski, Carlotta Giorgi, Roberto Ferrari, Lorenzo Galluzzi, Gianluca Campo, Paolo Pinton “New evidences on the pathological role of mitochondrial permeability transition pore in patients with STEMI” Cell Reports, 2021; Apr 13;35(2):108983. doi: 10.1016/j.celrep.2021.108983.; IF = 8.109

  • Ines C. M. Simoes, Agnieszka Karkucinska‐Wieckowska, Justyna Janikiewicz, Sylwia Szymanska, Maciej Pronicki, Pawel Dobrzyn, Michal Dabrowski, Agnieszka Dobrzyn, Paulo J. Oliveira, Hans Zischka, Yaiza Potes* and Mariusz R. Wieckowski* "Western Diet Causes Obesity‐Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response" (* - These authors share senior authorship) Antioxidants 2020, 9, 995; doi:10.3390/antiox9100995; IF= 5.033

  • Alberto Danese, Saverio Marchi, Veronica Angela Maria Vitto, Lorenzo Modesti, Sara Leo, Mariusz R. Wieckowski, Carlotta Giorgi and Paolo Pinton “Cancer-related increases and decreases in calcium signaling at the ER-mitochondria interface (MAM)” Reviews of Physiology, Biochemistry and Pharmacology (2020) – accepted; doi: 10.1007/112_2020_43; IF= 6.214

  • Gaia Pedriali, Giampaolo Morciano, Simone Patergnani, Paolo Cimaglia, Cristina Morelli, Elisa Mikus, Roberto Ferrari, Mariusz R Wieckowski and Paolo Pinton “Aortic valve stenosis and mitochondrial dysfunctions: clinical and molecular perspectives” International Journal of Molecular Sciences 2020 Jul 11;21(14):4899. doi: 10.3390/ijms21144899.; IF= 4.556

  • Massimo Bonora , Simone Patergnani, Daniela Ramaccini, Giampaolo Morciano, Gaia Pedriali, Asrat Kahsay, Esamaa Bouhamida, Carlotta Giorgi, Mariusz R. Więckowski*, Paolo Pinton* “Physiopathology of the permeability transition pore: Molecular mechanisms in human pathology.” (* - These authors share senior authorship); Biomolecules 2020 Jul 4;10(7):998. doi: 10.3390/biom10070998; IF= 4.082

  • Alessandro Rimessi, Chiara Pozzato, Lorenzo Carparelli, Alice Rossi, Serena Ranucci, Ida De Fino, Cristina Cigana, Anna Talarico, Mariusz R. Wieckowski, Carla M. P. Ribeiro, Claudio Trapella, Giacomo Rossi, Giulio Cabrini, Alessandra Bragonzi and Paolo Pinton “Pharmacological modulation of Mitochondrial Calcium Uniporter controls lung inflammation in cystic fibrosis” Science Advances – 2020, Vol. 6, no. 19, eaax9093; DOI: 10.1126/sciadv.aax9093; IF= 12.53

  • Ines C Simoes; Giampaolo Morciano; Magdalena Lebiedzinska-Arciszewska; Gianluca Aguiari; Paolo Pinton; Yaiza Potes; Mariusz R. Wieckowski “The mystery of mitochondria - ER contact sites in physiology and pathology: A cancer perspective” BBA - Molecular Basis of Disease - 2020 May 11;1866(10):165834; IF= 4.328

  • Merel Adjobo-Hermans; Ria de Haas; Peter H Willems; Aleksandra Wojtala; Sjenet E van Emst-de Vries; Jori A Wagenaars; Mariel van den Brand; Richard J Rodenburg; Jan A Smeitink; Leo G Nijtmans; Leonid A Sazanov; Mariusz R Wieckowski*; Werner J Koopman* “NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4-/- mice and Leigh syndrome patients: A stabilizing role for NDUFAF2” BBA – Bioenergeticsi2020 Apr 23;1861(8):148213 (* - corresponding authors); IF= 4.441

  • Claudia Morganti; Massimo Bonora; Saverio Marchi; Letizia Ferroni; Chiara Gardin; Mariusz R. Wieckowski; Carlotta Giorgi; Paolo Pinton; Barbara Zavan “Citrate mediates crosstalk between mitochondria and the nucleus to promote human mesenchymal stem cell in vitro osteogenesis” Cells 2020 Apr 21;9(4). pii: E1034. doi: 10.3390/cells9041034; IF= 5.656

  • Morciano G, Patergnani S, Bonora M, Pedriali G, Tarocco A, Bouhamida E, Marchi S, Ancora G, Anania G, Wieckowski MR, Giorgi C, Pinton P "Mitophagy in cardiovascular diseases" J. Clin. Med. 2020 Mar 24;9(3); IF = 5.688

  • Walczak J, Malińska D, Drabik K, Michalska B, Prill M, Johne S, Luettich K, Szymański J, Peitsch MC, Hoeng J, Duszyński J, Wieckowski MR, van der Toorn M, Szczepanowska J. "Mitochondrial Network and Biogenesis in Response to Short and Long-Term Exposure of Human BEAS-2B Cells to Aerosol Extracts from the Tobacco Heating System 2.2." Cell Physiol Biochem. 2020 Mar 11;54(2):230-251.

  • Perrone M, Caroccia N, Genovese I, Missiroli S, Modesti L, Pedriali G, Vezzani B, Vitto VAM, Antenori M, Lebiedzinska-Arciszewska M, Wieckowski MR, Giorgi C, Pinton P "The role of mitochondria-associated membranes in cellular homeostasis and diseases" Int. Rev. Cell Mol. Biol. (2020) - 2020; 350:119-196. IF = 3.788

  • Rimessi A, Pedriali G, Vezzani B, Tarocco A, Marchi S, Wieckowski MR, Giorgi C, Pinton P. "Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective" Semin Cell Dev Biol. 2020 Feb; 98:167-180. IF = 5.460

  • Simoes ICM, Janikiewicz J, Bauer J, Karkucinska-Wieckowska A, Kalinowski P, Dobrzyń A, Wolski A, Pronicki M, Zieniewicz K, Dobrzyń P, Krawczyk M, Zischka H, Wieckowski MR*, Potes Y*. "Fat and Sugar-A Dangerous Duet. A Comparative Review on Metabolic Remodeling in Rodent Models of Nonalcoholic Fatty Liver Disease". Nutrients. 2019 Nov 24;11(12). * - these authors share senior co-authorship

  • Malik AN, Simões ICM, Rosa HS, Khan S, Karkucinska-Wieckowska A, Wieckowski MR. "A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease" Cells. 2019 Oct 8;8(10). pii: E1222.

  • Malińska D, Więckowski MR, Michalska B, Drabik K, Prill M, Patalas-Krawczyk P, Walczak J, Szymański J, Mathis C, Van der Toorn M, Luettich K, Hoeng J, Peitsch MC, Duszyński J, Szczepanowska J. Mitochondria as a possible target for nicotine action. J Bioenerg Biomembr. 2019 Aug;51(4):259-276.

  • Marchi S, Vitto VAM, Danese A, Wieckowski MR, Giorgi C, Pinton P. Mitochondrial calcium uniporter complex modulation in cancerogenesis. Cell Cycle. 2019 May;18(10):1068-1083.

  • Tarocco A, Caroccia N, Morciano G, Wieckowski MR, Ancora G, Garani G, Pinton P. Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care. Cell Death Dis. 2019 Apr 8;10(4):317.

  • Pereira GC, Pereira SP, Pereira FB, Lourenço N, Lumini JA, Pereira CV, Bjork JA, Magalhães J, Ascensão A, Wieckowski MR, Moreno AJ, Wallace KB, Oliveira PJ. Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats. Toxicol Sci. 2019 May 1;169(1):137-150.

  • Flis DJ, Dzik K, Kaczor JJ, Cieminski K, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W. Swim Training Modulates Mouse Skeletal Muscle Energy Metabolism and Ameliorates Reduction in Grip Strength in a Mouse Model of Amyotrophic Lateral Sclerosis. Int J Mol Sci. 2019 Jan 9;20(2).

  • Grattagliano I, Montezinho LP, Oliveira PJ, Frühbeck G, Gómez-Ambrosi J, Montecucco F, Carbone F, Wieckowski MR, Wang DQ, Portincasa P. Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease. Biochem Pharmacol. 2019 Feb;160:34-45.

  • Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L. Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles. Nat Rev Cardiol. 2019 Jan;16(1):33-55.

  • Morganti C, Missiroli S, Lebiedzinska-Arciszewska M, Ferroni L, Morganti L, Perrone M, Ramaccini D, Occhionorelli S, Zavan B, Wieckowski MR, Giorgi C. Regulation of PKCβ levels and autophagy by PML is essential for high-glucose-dependent mesenchymal stem cell adipogenesis. Int J Obes (Lond). 2019 May;43(5):963-973.

  • Jędrak P, Mozolewski P, Węgrzyn G, Więckowski MR. Mitochondrial alterations accompanied by oxidative stress conditions in skin fibroblasts of Huntington's disease patients. Metab Brain Dis. 2018 Dec;33(6):2005-2017.

  • Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, Patalas-Krawczyk P, Borchard S, Jędrak P, Pierzynowska K, Szymański J, Wang DQ, Portincasa P, Węgrzyn G, Zischka H, Dobrzyn P, Bonora M, Duszynski J, Rimessi A, Karkucinska-Wieckowska A, Dobrzyn A, Szabadkai G, Zavan B, Oliveira PJ, Sardao VA, Pinton P, Wieckowski MR. Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases. Int Rev Cell Mol Biol. 2018; 340:209-344.

  • Morciano G, Preti D, Pedriali G, Aquila G, Missiroli S, Fantinati A, Caroccia N, Pacifico S, Bonora M, Talarico A, Morganti C, Rizzo P, Ferrari R, Wieckowski MR, Campo G, Giorgi C, Trapella C, Pinton P. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F(1)/F(O)-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61(16):7131-7143.

  • Flis DJ, Dzik K, Kaczor JJ, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W. Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice. Oxid Med Cell Longev. 2018 Apr 11;2018:5940748.

  • Morciano G, Marchi S, Morganti C, Sbano L, Bittremieux M, Kerkhofs M, Corricelli M, Danese A, Karkucinska-Wieckowska A, Wieckowski MR, Bultynck G, Giorgi C, Pinton P. Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings. Neoplasia. 2018 May;20(5):510-523.

  • Missiroli S, Patergnani S, Caroccia N, Pedriali G, Perrone M, Previati M, Wieckowski MR, Giorgi C. Mitochondria-associated membranes (MAMs) and inflammation. Cell Death Dis. 2018 Feb 28;9(3):329.

  • Janikiewicz J, Szymański J, Malinska D, Patalas-Krawczyk P, Michalska B, Duszyński J, Giorgi C, Bonora M, Dobrzyn A, Wieckowski MR. Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics. Cell Death Dis. 2018 Feb 28;9(3):332.

  • Malinska D, Szymański J, Patalas-Krawczyk P, Michalska B, Wojtala A, Prill M, Partyka M, Drabik K, Walczak J, Sewer A, Johne S, Luettich K, Peitsch MC, Hoeng J, Duszyński J, Szczepanowska J, van der Toorn M, Wieckowski MR. Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes. Food Chem Toxicol. 2018 May;115:1-12.

  • Simões ICM, Fontes A, Pinton P, Zischka H, Wieckowski MR. Mitochondria in non-alcoholic fatty liver disease. Int J Biochem Cell Biol. 2018 Feb;95:93-99.

  • Marchi S, Patergnani S, Missiroli S, Morciano G, Rimessi A, Wieckowski MR, Giorgi C, Pinton P. Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death. Cell Calcium. 2018 Jan;69:62-72.

  • Pedriali G, Rimessi A, Sbano L, Giorgi C, Wieckowski MR, Previati M, Pinton P. Regulation of Endoplasmic Reticulum-Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies. Front Oncol. 2017 Aug 31;7:180.

  • Wojtala A, Karkucinska-Wieckowska A, Sardao VA, Szczepanowska J, Kowalski P, Pronicki M, Duszynski J, Wieckowski MR. Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway. Mitochondrion. 2017 Nov;37:62-79.

  • Szymański J, Janikiewicz J, Michalska B, Patalas-Krawczyk P, Perrone M, Ziółkowski W, Duszyński J, Pinton P, Dobrzyń A, Więckowski MR. Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure. Int J Mol Sci. 2017 Jul 20;18(7). pii: E1576.

  • Bonora M, Morganti C, Morciano G, Pedriali G, Lebiedzinska-Arciszewska M, Aquila G, Giorgi C, Rizzo P, Campo G, Ferrari R, Kroemer G*, Wieckowski MR*, Galluzzi L*, Pinton P*. Mitochondrial permeability transition involves dissociation of F(1)F(O) ATP synthase dimers and C-ring conformation. EMBO Rep. 2017 Jul;18(7):1077-1089. * - these authors share senior co-authorship

  • Teixeira J, Chavarria D, Borges F, Wojtczak L, Wieckowski MR, Karkucińska-Wieckowska A, Oliveira PJ. Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease. Curr Med Chem. 2017 May 28. doi: 10.2174/0929867324666170529101810. [Epub ahead of print].

  • Morciano G, Bonora M, Campo G, Aquila G, Rizzo P, Giorgi C, Wieckowski MR, Pinton P. Mechanistic Role of mPTP in Ischemia-Reperfusion Injury. Adv Exp Med Biol. 2017; 982:169-189. doi: 10.1007/978-3-319-55330-6_9.

  • Danese A, Patergnani S, Bonora M, Wieckowski MR, Previati M, Giorgi C, Pinton P. Calcium regulates cell death in cancer: Roles of the mitochondria and mitochondria-associated membranes (MAMs). Biochim Biophys Acta (Bioenerg.) 2017 Aug;1858(8):615-627.

  • Patergnani S, Fossati V, Bonora M, Giorgi C, Marchi S, Missiroli S, Rusielewicz T, Wieckowski MR, Pinton P. Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis. Int Rev Cell Mol Biol. 2017; 328:49-103.

  • Del Prete D, Suski JM, Oulès B, Debayle D, Gay AS, Lacas-Gervais S, Bussiere R, Bauer C, Pinton P, Paterlini-Bréchot P, Wieckowski MR, Checler F, Chami M. Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes. J Alzheimers Dis. 2017; 55(4):1549-1570.

  • Diogo CV, Deus CM, Lebiedzinska-Arciszewska M, Wojtala A, Wieckowski MR, Oliveira PJ. Carvedilol and antioxidant proteins in a type I diabetes animal model. Eur J Clin Invest. 2017 Jan;47(1):19-29.

  • Oparka M, Walczak J, Malinska D, van Oppen LMPE, Szczepanowska J, Koopman WJH, Wieckowski MR. Quantifying ROS levels using CM-H(2)DCFDA and HyPer. Methods. 2016 Oct 15;109:3-11.

  • Rimessi A, Previati M, Nigro F, Wieckowski MR*, Pinton P*. Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies. Int J Biochem Cell Biol. 2016 Dec;81(Pt B):281-293. * - these authors share senior co-authorship

  • Bonora M, Morganti C, Morciano G, Giorgi C, Wieckowski MR, Pinton P. Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques. Nat Protoc. 2016 Jun;11(6):1067-80.

  • Giorgi C, Bonora M, Missiroli S, Morganti C, Morciano G, Wieckowski MR, Pinton P. Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants. Front Oncol. 2016 Feb 25;6:42. doi: 10.3389/fonc.2016.00042. eCollection 2016.

  • Wojtczak L, Więckowski MR. From mitochondrial large amplitude swelling to the permeability transition - a short historic overview. Postepy Biochem. 2016; 62(3):298-302.

  • Sampaio SF, Branco AF, Wojtala A, Vega-Naredo I, Wieckowski MR, Oliveira PJ. p66Shc signaling is involved in stress responses elicited by anthracycline treatment of rat cardiomyoblasts. Arch Toxicol. 2016 Jul;90(7):1669-84.

  • Wieckowski MR, Deus CM, Couto R, Oparka M, Lebiedzińska-Arciszewska M, Duszyński J, Oliveira PJ. Measuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells. Curr Protoc Toxicol. 2015 Nov 2;66:25.6.1-21

  • Rimessi A, Patergnani S, Bonora M, Wieckowski MR, Pinton P. Mitochondrial Ca2+ Remodeling is a Prime Factor in Oncogenic Behavior. Front Oncol. 2015 Jun 25;5:143. doi: 10.3389/fonc.2015.00143. eCollection 2015.

  • Giorgi C, Bonora M, Sorrentino G, Missiroli S, Poletti F, Suski JM, Galindo Ramirez F, Rizzuto R, Di Virgilio F, Zito E, Pandolfi PP, Wieckowski MR, Mammano F, Del Sal G, Pinton P. p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1779-84.

  • Giorgi C, Missiroli S, Patergnani S, Duszynski J, Wieckowski MR*, Pinton P* Mitochondria-associated membranes: composition, molecular mechanisms, and physiopathological implications. Antioxid Redox Signal. 2015 Apr 20;22(12):995-1019. * - these authors share senior co-authorship

  • Distelmaier F, Valsecchi F, Liemburg-Apers DC, Lebiedzinska M, Rodenburg RJ, Heil S, Keijer J, Fransen J, Imamura H, Danhauser K, Seibt A, Viollet B, Gellerich FN, Smeitink JA, Wieckowski MR, Willems PH, Koopman WJ. Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α. Biochim Biophys Acta. 2015 Mar;1852(3):529-40.

  • Lebiedzinska-Arciszewska M, Oparka M, Vega-Naredo I, Karkucinska-Wieckowska A, Pinton P, Duszynski J, Wieckowski MR. The interplay between p66Shc, reactive oxygen species and cancer cell metabolism. Eur J Clin Invest. 2015 Jan;45 Suppl 1:25-31.

  • Karkucinska-Wieckowska A, Pronicki M, Wieckowski MR. Histoenzymatic methods for visualization of the activity of individual mitochondrial respiratory chain complexes in the muscle biopsies from patients with mitochondrial defects. Methods Mol Biol. 2015; 1241:85-93.

  • Wieckowski MR, Wojtczak L. Isolation of crude mitochondrial fraction from cells. Methods Mol Biol. 2015; 1241:1-8.

  • Bonora M, Wieckowski MR, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, Pinton P. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015 Mar 19;34(12):1475-86.

  • Morciano G, Giorgi C, Bonora M, Punzetti S, Pavasini R, Wieckowski MR, Campo G, Pinton P. Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury. J Mol Cell Cardiol. 2015 Jan;78:142-53.

  • Camporeale A, Demaria M, Monteleone E, Giorgi C, Wieckowski MR, Pinton P, Poli V. STAT3 Activities and Energy Metabolism: Dangerous Liaisons. Cancers (Basel). 2014 Jul 31;6(3):1579-96.

  • Patergnani S, Baldassari F, De Marchi E, Karkucinska-Wieckowska A, Wieckowski MR, Pinton P. Methods to monitor and compare mitochondrial and glycolytic ATP production. Methods Enzymol. 2014; 542:313-32.

  • Wojtala A, Bonora M, Malinska D, Pinton P, Duszynski J, Wieckowski MR. Methods to monitor ROS production by fluorescence microscopy and fluorometry. Methods Enzymol. 2014; 542:243-62.

  • Forkink M, Manjeri GR, Liemburg-Apers DC, Nibbeling E, Blanchard M, Wojtala A, Smeitink JA, Wieckowski MR, Willems PH, Koopman WJ. Mitochondrial hyperpolarization during chronic complex I inhibition is sustained by low activity of complex II, III, IV and V. Biochim Biophys Acta. 2014 Aug;1837(8):1247-56.

  • Marchi S, Giorgi C, Oparka M, Duszynski J, Wieckowski MR, Pinton P. Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes. Mol Cell Oncol. 2014 Oct 29;1(2):e956469. doi: 10.4161/23723548.2014.956469. eCollection 2014

  • Bonora M, De Marchi E, Patergnani S, Suski JM, Celsi F, Bononi A, Giorgi C, Marchi S, Rimessi A, Duszyński J, Pozzan T, Wieckowski MR*, Pinton P*. Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process. Cell Death Differ. 2014 Aug;21(8):1198-208. * - these authors share senior co-authorship

  • Suski JM, Lebiedzinska M, Wojtala A, Duszynski J, Giorgi C, Pinton P, Wieckowski MR. Isolation of plasma membrane-associated membranes from rat liver. Nat Protoc. 2014 Feb;9(2):312-22.

  • Piekutowska-Abramczuk D, Pronicki M, Strawa K, Karkucińska-Więckowska A, Szymańska-Dębińska T, Fidziańska A, Więckowski MR, Jurkiewicz D, Ciara E, Jankowska I, Sykut-Cegielska J, Krajewska-Walasek M, Płoski R, Pronicka E. Novel c.191C>G (p.Pro64Arg) MPV17 mutation identified in two pairs of unrelated Polish siblings with mitochondrial hepatoencephalopathy. Clin Genet. 2014 Jun;85(6):573-7.

  • Bednarczyk P, Wieckowski MR, Broszkiewicz M, Skowronek K, Siemen D, Szewczyk A. Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain. PLoS One. 2013 Jun 27;8(6):e68125.

  • Branco AF, Sampaio SF, Wieckowski MR, Sardão VA, Oliveira PJ. Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: differential activation of stress and survival pathways. Int J Biochem Cell Biol. 2013 Nov;45(11):2379-91.

  • De Marchi E, Baldassari F, Bononi A, Wieckowski MR, Pinton P. Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C. Oxid Med Cell Longev. 2013; 2013:564961.

  • Karkucinska-Wieckowska A, Trubicka J, Werner B, Kokoszynska K, Pajdowska M, Pronicki M, Czarnowska E, Lebiedzinska M, Sykut-Cegielska J, Ziolkowska L, Jaron W, Dobrzanska A, Ciara E, Wieckowski MR, Pronicka E. Left ventricular noncompaction (LVNC) and low mitochondrial membrane potential are specific for Barth syndrome. J Inherit Metab Dis. 2013 Nov;36(6):929-37.

  • Bonora M, Bononi A, De Marchi E, Giorgi C, Lebiedzinska M, Marchi S, Patergnani S, Rimessi A, Suski JM, Wojtala A, Wieckowski MR*, Kroemer G*, Galluzzi L*, Pinton P*. Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. Cell Cycle. 2013 Feb 15;12(4):674-83* - these authors share senior co-authorship

  • Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczynski G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Ježek P, Pronicki M, Duszynski J, Pinton P, Wieckowski MR. Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients. Int J Biochem Cell Biol. 2013 Jan;45(1):141-50.

  • Yao Z, Jones AW, Fassone E, Sweeney MG, Lebiedzinska M, Suski JM, Wieckowski MR, Tajeddine N, Hargreaves IP, Yasukawa T, Tufo G, Brenner C, Kroemer G, Rahman S, Szabadkai G. PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations. Oncogene. 2013 May 16;32(20):2592-600.

  • Diogo CV, Suski JM, Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Pronicki M, Duszynski J, Pinton P, Portincasa P, Oliveira PJ, Wieckowski MR. Cardiac mitochondrial dysfunction during hyperglycemia -the role of oxidative stress and p66Shc signaling. Int J Biochem Cell Biol. 2013 Jan;45(1):114-22.

  • Suski JM, Schönfeld P, Bonora M, Shabalina I, Pinton P, Więckowski MR. Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: new evidence for a putative novel function of uncoupling proteins as superoxide anion transporters. Biochem Biophys Res Commun. 2012 Nov 16;428(2):234-8.

  • Bonora M, Patergnani S, Rimessi A, De Marchi E, Suski JM, Bononi A, Giorgi C, Marchi S, Missiroli S, Poletti F, Wieckowski MR, Pinton P. ATP synthesis and storage. Purinergic Signal. 2012 Sep;8(3):343-57.

  • Giorgi C, Baldassari F, Bononi A, Bonora M, De Marchi E, Marchi S, Missiroli S, Patergnani S, Rimessi A, Suski JM, Wieckowski MR, Pinton P. Mitochondrial Ca2+ and apoptosis. Cell Calcium. 2012 Jul;52(1):36-43.

  • Bononi A, Missiroli S, Poletti F, Suski JM, Agnoletto C, Bonora M, De Marchi E, Giorgi C, Marchi S, Patergnani S, Rimessi A, Wieckowski MR, Pinton P. Mitochondria-associated membranes (MAMs) as hotspot Ca2+ signaling units. Adv Exp Med Biol. 2012; 740:411-37.

  • Szczepanowska J, Malinska D, Wieckowski MR, Duszynski J. Effect of mtDNA point mutations on cellular bioenergetics. Biochim Biophys Acta. 2012 Oct;1817(10):1740-6.

  • Marchi S, Giorgi C, Suski JM, Agnoletto C, Bononi A, Bonora M, De Marchi E, Missiroli S, Patergnani S, Poletti F, Rimessi A, Duszynski J, Wieckowski MR, Pinton P. Mitochondria-ros crosstalk in the control of cell death and aging. J Signal Transduct. 2012; 2012:329635.

  • Suski JM, Lebiedzinska M, Bonora M, Pinton P, Duszynski J, Wieckowski MR. Relation between mitochondrial membrane potential and ROS formation. Methods Mol Biol. 2012; 810:183-205.

  • Giorgi C, Agnoletto C, Bononi A, Bonora M, De Marchi E, Marchi S, Missiroli S, Patergnani S, Poletti F, Rimessi A, Suski JM, Wieckowski MR, Pinton P. Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. Mitochondrion. 2012 Jan;12(1):77-85.

  • Pereira CV, Lebiedzinska M, Wieckowski MR, Oliveira PJ. Regulation and protection of mitochondrial physiology by sirtuins. Mitochondrion. 2012 Jan;12(1):66-76.

  • Giorgi C, Wieckowski MR, Pandolfi PP, Pinton P. Mitochondria associated membranes (MAMs) as critical hubs for apoptosis. Commun Integr Biol. 2011 May;4(3):334-5.

  • Suski JM, Karkucinska-Wieckowska A, Lebiedzinska M, Giorgi C, Szczepanowska J, Szabadkai G, Duszynski J, Pronicki M, Pinton P, Wieckowski MR. p66Shc aging protein in control of fibroblasts cell fate. Int J Mol Sci. 2011; 12(8):5373-89.

  • Patergnani S, Suski JM, Agnoletto C, Bononi A, Bonora M, De Marchi E, Giorgi C, Marchi S, Missiroli S, Poletti F, Rimessi A, Duszynski J, Wieckowski MR, Pinton P. Calcium signaling around Mitochondria Associated Membranes (MAMs). Cell Commun Signal. 2011 Sep 22;9:19.

  • Karkucinska-Wieckowska A, Lebiedzinska M, Jurkiewicz E, Pajdowska M, Trubicka J, Szymanska-Debinska T, Suski J, Pinton P, Duszynski J, Pronicki M, Wieckowski MR, Pronicka E. Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria). Folia Neuropathol. 2011; 49(1):56-63.

  • Wojtczak L, Lebiedzińska M, Suski JM, Więckowski MR, Schönfeld P. Inhibition by purine nucleotides of the release of reactive oxygen species from muscle mitochondria: indication for a function of uncoupling proteins as superoxide anion transporters. Biochem Biophys Res Commun. 2011 Apr 22;407(4):772-6.

  • Suski J, Lebiedzinska M, Machado NG, Oliveira PJ, Pinton P, Duszynski J, Wieckowski MR. Mitochondrial tolerance to drugs and toxic agents in ageing and disease. Curr Drug Targets. 2011 Jun;12(6):827-49.

  • Demaria M, Giorgi C, Lebiedzinska M, Esposito G, D'Angeli L, Bartoli A, Gough DJ, Turkson J, Levy DE, Watson CJ, Wieckowski MR, Provero P, Pinton P, Poli V. A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction. Aging (Albany NY). 2010 Nov;2(11):823-42.

  • Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P, Pandolfi PP. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science. 2010 Nov 26;330(6008):1247-51.

  • Ziolkowski W, Szkatula M, Nurczyk A, Wakabayashi T, Kaczor JJ, Olek RA, Knap N, Antosiewicz J, Wieckowski MR, Wozniak M. Methyl-beta-cyclodextrin induces mitochondrial cholesterol depletion and alters the mitochondrial structure and bioenergetics. FEBS Lett. 2010 Nov 19;584(22):4606-10.

  • Lebiedzińska M, Suski J, Duszyński J, Wieckowski MR. [Role of the p66Shc protein in physiological state and in pathologies]. Postepy Biochem. 2010; 56(2):165-73.

  • Nowis D, Maczewski M, Mackiewicz U, Kujawa M, Ratajska A, Wieckowski MR, Wilczyński GM, Malinowska M, Bil J, Salwa P, Bugajski M, Wójcik C, Siński M, Abramczyk P, Winiarska M, Dabrowska-Iwanicka A, Duszyński J, Jakóbisiak M, Golab J. Cardiotoxicity of the anticancer therapeutic agent bortezomib. Am J Pathol. 2010 Jun;176(6):2658-68.

  • Lebiedzinska M, Karkucinska-Wieckowska A, Giorgi C, Karczmarewicz E, Pronicka E, Pinton P, Duszynski J, Pronicki M, Wieckowski MR. Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):952-60.

  • Schönfeld P, Wieckowski MR, Lebiedzińska M, Wojtczak L. Mitochondrial fatty acid oxidation and oxidative stress: lack of reverse electron transfer-associated production of reactive oxygen species. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):929-38.

  • Wieckowski MR, Giorgi C, Lebiedzinska M, Duszynski J, Pinton P. Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells. Nat Protoc. 2009 ;4(11):1582-90.

  • Lebiedzinska M, Szabadkai G, Jones AW, Duszynski J, Wieckowski MR. Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles. Int J Biochem Cell Biol. 2009 Oct;41(10):1805-16.

  • Kozieł K, Lebiedzinska M, Szabadkai G, Onopiuk M, Brutkowski W, Wierzbicka K, Wilczyński G, Pinton P, Duszyński J, Zabłocki K, Wieckowski MR. Plasma membrane associated membranes (PAM) from Jurkat cells contain STIM1 protein is PAM involved in the capacitative calcium entry? Int J Biochem Cell Biol. 2009 Dec;41(12):2440-9.

  • Lebiedzinska M, Duszynski J, Rizzuto R, Pinton P, Wieckowski MR. Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues. Arch Biochem Biophys. 2009 Jun 1;486(1):73-80.

  • Lebiedzińska M, Duszyński J, Wieckowski MR. [Application of "blue native" electrophoresis in the studies of mitochondrial respiratory chain complexes in physiology and pathology]. Postepy Biochem. 2008; 54(2):217-23.

  • Wieckowski MR. [The role of mitochondrial permeability transition pore in physiology and pathology of the cell]. Postepy Biochem. 2008; 54(1):71-81.

  • Campanella M, Casswell E, Chong S, Farah Z, Wieckowski MR, Abramov AY, Tinker A, Duchen MR. Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1. Cell Metab. 2008 Jul;8(1):13-25.

  • Belyaeva EA, Dymkowska D, Wieckowski MR, Wojtczak L. Mitochondria as an important target in heavy metal toxicity in rat hepatoma AS-30D cells. Toxicol Appl Pharmacol. 2008 Aug 15;231(1):34-42.

  • Pinton P, Rimessi A, Marchi S, Orsini F, Migliaccio E, Giorgio M, Contursi C, Minucci S, Mantovani F, Wieckowski MR, Del Sal G, Pelicci PG, Rizzuto R. Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science. 2007 Feb 2;315(5812):659-63.

  • Szabadkai G, Bianchi K, Várnai P, De Stefani D, Wieckowski MR, Cavagna D, Nagy AI, Balla T, Rizzuto R. Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. J Cell Biol. 2006 Dec 18;175(6):901-11.

  • Belyaeva EA, Dymkowska D, Wieckowski MR, Wojtczak L. Reactive oxygen species produced by the mitochondrial respiratory chain are involved in Cd2+-induced injury of rat ascites hepatoma AS-30D cells. Biochim Biophys Acta. 2006 Dec;1757(12):1568-74.

  • Wieckowski MR, Szabadkai G, Wasilewski M, Pinton P, Duszyński J, Rizzuto R. Overexpression of adenine nucleotide translocase reduces Ca2+ signal transmission between the ER and mitochondria. Biochem Biophys Res Commun. 2006 Sep 22;348(2):393-9.

  • Szabadkai G, Simoni AM, Bianchi K, De Stefani D, Leo S, Wieckowski MR, Rizzuto R. Mitochondrial dynamics and Ca2+ signaling. Biochim Biophys Acta. 2006 May-Jun;1763(5-6):442-9.

  • Dymkowska D, Szczepanowska J, Wieckowski MR, Wojtczak L. Short-term and long-term effects of fatty acids in rat hepatoma AS-30D cells: the way to apoptosis. Biochim Biophys Acta. 2006 Feb;1763(2):152-63.

  • Szondy Z, Mastroberardino PG, Váradi J, Farrace MG, Nagy N, Bak I, Viti I, Wieckowski MR, Melino G, Rizzuto R, Tósaki A, Fesus L, Piacentini M. Tissue transglutaminase (TG2) protects cardiomyocytes against ischemia/reperfusion injury by regulating ATP synthesis. Cell Death Differ. 2006 Oct;13(10):1827-9.

  • Adinolfi E, Callegari MG, Ferrari D, Bolognesi C, Minelli M, Wieckowski MR, Pinton P, Rizzuto R, Di Virgilio F. Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. Mol Biol Cell. 2005 Jul;16(7):3260-72.

  • Szabadkai G, Simoni AM, Chami M, Wieckowski MR, Youle RJ, Rizzuto R. Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis. Mol Cell. 2004 Oct 8;16(1):59-68.

  • Wasilewski M, Wieckowski MR, Dymkowska D, Wojtczak L. Effects of N-acylethanolamines on mitochondrial energetics and permeability transition. Biochim Biophys Acta. 2004 Jul 9;1657(2-3):151-63.

  • Pinton P, Leo S, Wieckowski MR, Di Benedetto G, Rizzuto R. Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes. J Cell Biol. 2004 Apr 26;165(2):223-32.

  • Rapizzi E, Pinton P, Szabadkai G, Wieckowski MR, Vandecasteele G, Baird G, Tuft RA, Fogarty KE, Rizzuto R. Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria. J Cell Biol. 2002 Nov 25;159(4):613-24.

  • Wieckowski MR, Vyssokikh M, Dymkowska D, Antonsson B, Brdiczka D, Wojtczak L. Oligomeric C-terminal truncated Bax preferentially releases cytochrome c but not adenylate kinase from mitochondria, outer membrane vesicles and proteoliposomes. FEBS Lett. 2001 Sep 21;505(3):453-9.

  • Wieckowski MR, Brdiczka D, Wojtczak L. Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore. FEBS Lett. 2000 Nov 3;484(2):61-4.

  • Schönfeld P, Wieckowski MR, Wojtczak L. Long-chain fatty acid-promoted swelling of mitochondria: further evidence for the protonophoric effect of fatty acids in the inner mitochondrial membrane. FEBS Lett. 2000 Apr 7;471(1):108-12.

  • Wojtczak L, Wieckowski MR. The mechanisms of fatty acid-induced proton permeability of the inner mitochondrial membrane. J Bioenerg Biomembr. 1999 Oct;31(5):447-55.

  • Wojtczak L, Teplova VV, Bogucka K, Czyz A, Makowska A, Wieckowski MR, Duszyński J, Evtodienko YV. Effect of glucose and deoxyglucose on the redistribution of calcium in ehrlich ascites tumour and Zajdela hepatoma cells and its consequences for mitochondrial energetics. Further arguments for the role of Ca2+ in the mechanism of the crabtree effect. Eur J Biochem. 1999 Jul;263(2):495-501.

  • Piwocka K, Zabłocki K, Wieckowski MR, Skierski J, Feiga I, Szopa J, Drela N, Wojtczak L, Sikora E. A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells. Exp Cell Res. 1999 Jun 15;249(2):299-307.

  • Wojtczak L, Wieckowski MR, Schönfeld P. Protonophoric activity of fatty acid analogs and derivatives in the inner mitochondrial membrane: a further argument for the fatty acid cycling model. Arch Biochem Biophys. 1998 Sep 1;357(1):76-84.

  • Wieckowski MR, Wojtczak L. Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore. FEBS Lett. 1998 Feb 27;423(3):339-42.

  • Schönfeld P, Więckowski MR, Wojtczak L. Thyroid hormone-induced expression of the ADP/ATP carrier and its effect on fatty acid-induced uncoupling of oxidative phosphorylation. FEBS Lett. 1997 Oct 13;416(1):19-22.

  • Wieckowski MR, Wojtczak L. Involvement of the dicarboxylate carrier in the protonophoric action of long-chain fatty acids in mitochondria. Biochem Biophys Res Commun. 1997 Mar 17;232(2):414-7.

  • Schönfeld P, Jezek P, Belyaeva EA, Borecký J, Slyshenkov VS, Wieckowski MR, Wojtczak L. Photomodification of mitochondrial proteins by azido fatty acids and its effect on mitochondrial energetics. Further evidence for the role of the ADP/ATP carrier in fatty-acid-mediated uncoupling. Eur J Biochem. 1996 Sep 1;240(2):387-93.

  • Wieckowski MR, Zabłocki K. [Osmolytes and osmoregulation in renal cells]. Postepy Biochem. 1996; 42(2):167-77.